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Dysregulated miR-124 mediates impaired social memory behavior caused by paternal early social isolation
Nature
This study has discovered that paternal early SI causes social memory deficits and anxiety-like behavior in F1 young adult mice.
1 month ago
Elocution, Or Mental and Vocal Philosophy: Involving the Principles of ... - C. P. Bronson
Google Llibres
Involving the principles of reading and speaking; and designed for the development and cultivation of both body and mind.
1 month ago
Full article: Folate-mediated transgenerational inheritance of sperm DNA methylation patterns correlate with spinal axon regeneration
Taylor & Francis Online: Peer-reviewed Journals
Ancestral environmental exposures influence the phenotypes of consecutive generations of unexposed offspring in the absence of corresponding DNA sequence...
3 months ago
Full article: Transgenerational epigenetic self-memory of Dio3 dosage is associated with Meg3 methylation and altered growth trajectories and neonatal hormones
Taylor & Francis Online: Peer-reviewed Journals
Our results provide a novel paradigm of epigenetic self-memory by which Dio3 gene dosage in a given individual, and its dependent developmental exposure to...
3 months ago
Revisiting Epigenetics Fundamentals and Its Biomedical Implications
MDPI
In light of the post-genomic era, epigenetics brings about an opportunity to better understand how the molecular machinery works and is led by a complex...
3 months ago
Paternal Contributions to Offspring Health: Role of Sperm Small RNAs in Intergenerational Transmission of Epigenetic Information
Frontiers
Here, I review some of the concepts, evidence, and mechanisms of intergenerational epigenetic inheritance via sperm small RNAs.
4 months ago
Epigenetic Inheritance: Concepts, Mechanisms and Perspectives
Frontiers
In this work, we systematize the concept of epigenetic inheritance, discuss the putative mechanisms, and recapitulate the methods for studying this...
4 months ago
Germ Cell Drivers: Transmission of Preconception Stress Across Generations
Frontiers
Emerging evidence primarily from preclinical models suggests that epigenetic programming may encode preconception stress exposures in germ cells.
4 months ago
From Sperm Motility to Sperm-Borne microRNA Signatures: New Approaches to Predict Male Fertility Potential
Frontiers
In addition to the paternal genome, spermatozoa carry several intrinsic factors, including organelles (e.g., centrioles and mitochondria) and molecules...
4 months ago
Stress and the Emerging Roles of Chromatin Remodeling in Signal Integration and Stable Transmission of Reversible Phenotypes
Frontiers
In this review article, we discuss the potential molecular mechanism(s) of gene regulation associated with chromatin modeling and programming.
4 months ago